Associations of Lifetime Cognitive Enrichment With Incident Alzheimer Disease Dementia, Cognitive Aging, and Cognitive Resilience
Lifetime exposure to cognitive enrichment was related to lower risk of AD dementia and a slower rate of cognitive decline, including after adjustment for common ADRD pathologies, indicating higher resilience provided by lifetime enrichment. Our results suggest that cognitive health in later life is in part the product of lifetime exposure to cognitive enrichment.
Authors
- Victoria N. Poole (ORCID: https://orcid.org/0000-0003-0974-2564)
- Alifiya Kapasi
- Robert S. Wilson
- Andrea R. Zammit
- Lei Yu
- David A. Bennett
Institutions
- Rush University Medical Center (US)
Publication Details
- Journal
- Neurology
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1212/wnl.0000000000214677
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 33.12