Investigating <scp>human platelet</scp> antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

Referral patterns and laboratory findings from NPIRL demonstrate a marked discrepancy between expected FNAIT incidence and observed diagnostic activity in Canada, indicating that FNAIT is substantially under-identified. These findings highlight the need for improved recognition, standardized investigation pathways and enhanced diagnostic strategies to reduce missed cases and improve neonatal outcomes.

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Publication Details

Journal
Vox Sanguinis
Published
2026-02-11
DOI
https://doi.org/10.1111/vox.70210
Primary Topic
Platelet Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Investigating human platelet antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

Bryan Tordon, Gwen Clarke, Jacqueline Wong, Akash Gupta et al.
Vox Sanguinis
Platelet Disorders and Treatments
article

Investigating human platelet antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

Bryan Tordon, Gwen Clarke, Jacqueline Wong, Akash Gupta, Ann Peregrin
article en

Abstract

Referral patterns and laboratory findings from NPIRL demonstrate a marked discrepancy between expected FNAIT incidence and observed diagnostic activity in Canada, indicating that FNAIT is substantially under-identified. These findings highlight the need for improved recognition, standardized investigation pathways and enhanced diagnostic strategies to reduce missed cases and improve neonatal outcomes.

Vox Sanguinis
University of Alberta (CA), University of Calgary (CA), University of Toronto (CA), Canadian Blood Services (CA)
Good health and well-being
Openalex Percentile: Top 58%
Platelet Disorders and Treatments
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