The Influence of Circadian Onset Time on Admission Severity in Acute Ischemic Stroke: A Retrospective Cohort Study
Admission stroke severity follows a circadian pattern, with milder presentations in the Morning and more severe impairments during Night hours. These findings highlight the potential role of circadian biology in stroke pathophysiology and support incorporating time-of-onset considerations into clinical risk stratification and acute management strategies.
Authors
- Shiyu Hu
- Yuqi Liao (ORCID: https://orcid.org/0000-0002-4663-1815)
- Lu Ren (ORCID: https://orcid.org/0000-0002-2166-1030)
- Shaoling Li
- Manjuan Yao
Institutions
- Federal State Budgetary Institution "Center for Expertise and Quality Control of Medical Care" (RU)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Journal of Central Nervous System Disease
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1177/11795735261421368
- Primary Topic
- Climate Change and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00