Dendrimeric Antigens for Passive Mast Cell Activation in the Evaluation of Amoxicillin Allergy
DeAns are effective platforms for investigating effector cell activation in AX allergy. By fine-tuning structural attributes-size and multivalence-we reveal the promising utility of DeAns in pMAT that leverage commercial cell lines and patient sera. This approach could address key limitations of β-lactam allergy diagnostics, enabling more reliable and standardized in vitro testing.
Authors
- María Jesús Rodríguez‐Sojo (ORCID: https://orcid.org/0000-0002-1693-505X)
- C. Mayorga (ORCID: https://orcid.org/0000-0001-8852-8077)
- Juan L. Paris (ORCID: https://orcid.org/0000-0001-8950-283X)
- Amene Tesfaye Ayane (ORCID: https://orcid.org/0000-0003-0482-8895)
- Isabel Jiménez (ORCID: https://orcid.org/0000-0003-4971-0612)
- María Belén Salas
- Sara Benedé (ORCID: https://orcid.org/0000-0002-9288-9438)
- María Jesús Rodríguez‐Sánchez
- Torres
- María Montañez
- Alba Rodríguez‐Nogales
- Gador Bogas
- Ezequiel Perez‐Inestrosa
Institutions
- Universidad de Granada (ES)
- Hospital Regional Universitario de Málaga (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Instituto de Investigación en Ciencias de la Alimentación (ES)
- Andalusian Centre for Nanomedicine and Biotechnology (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- Universidad Autónoma de Madrid (ES)
- Universidad de Málaga (ES)
Publication Details
- Journal
- Allergy
- Published
- 2026-02-11
- DOI
- https://doi.org/10.1111/all.70250
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad de Málaga
- Ministerio de Ciencia, Innovación y Universidades
- European Commission
- Ministerio de Ciencia e Innovación
- Junta de Andalucía
- Horizon 2020 Framework Programme
- Instituto de Salud Carlos III
- Agencia Estatal de Investigación