Numerical Simulation of a Bulk Superconductor-Based Millifluidic Magnetic Separation Chip

The separation of magnetic micro- and nanoparticles based on their size and magnetic properties can greatly enhance their potential in chemical, biological, and medical applications. In this work, we propose a millifluidic magnetic separation chip that employs a bulk superconducting magnet to achieve efficient particle separation. The separation performance of the chip is analysed using the finite-element software package COMSOL Multiphysics. The performance of the chip is investigated under different magnetic conditions, including the use of a permanent magnet and bulk superconducting magnets operating at various temperatures. The results demonstrate that at a bulk operating temperature of 60 K, the system can effectively achieve high-throughput separation of μm-sized magnetic particles with diameters up to 20 μm. The study also reveals that the chip can be utilised for particle size detection. Overall, this modelling framework provides a theoretical foundation for the design and development of practical, high-efficiency mil-lifluidic magnetic separation systems for future applications.