Genetic polymorphisms of the CDC27 gene are associated with susceptibility and outcomes of non-syndromic congenital heart disease: a bi-ethnic case–control study in Chinese populations
The <i>CDC27</i> rs11570579 polymorphism is associated with susceptibility to CHD in the Uyghur population of Xinjiang. The rs11570488 polymorphism is associated with PASP, cardiac remodeling, and long-term mortality in patients with CHD.
Authors
- Aikebai Aisan
- Tunike Maheshati
- Teng Yuan (ORCID: https://orcid.org/0000-0002-9692-3998)
- You Chen (ORCID: https://orcid.org/0000-0002-2869-2577)
- Yunxia Li
- Ren Tian
- Feng Zhu
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Changshu No.1 People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2026-02-11
- DOI
- https://doi.org/10.3389/fgene.2026.1701812
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Xinjiang