Quadruple vs triple therapy for resistant hypertension: the QUADRO trial
The first full-dose quadruple antihypertensive SPC (perindopril/indapamide/amlodipine/bisoprolol) demonstrated superiority over perindopril/indapamide/amlodipine, offering an effective alternative therapy for confirmed resistant hypertension.
Authors
- Parvoleta Petrova
- Stéphanie Bricout-Hennel
- Cécile Batailler (ORCID: https://orcid.org/0000-0003-3990-0906)
- K Narkiewicz
- S Taddei
- Roland Asmar
Institutions
- University of Pisa (IT)
- Institut des Sciences du Végétal (FR)
- Servier (France) (FR)
- Medical Research Foundation (GB)
- Gdańsk Medical University (PL)
Publication Details
- Journal
- European Heart Journal
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1093/eurheartj/ehag022
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00