A Double-Blinded, Split-Face Clinical Trial Evaluating the Effects of a Vitamin C, E, and Ferulic Acid Serum Combined with Microneedling on Facial Photoaging
Combining topical antioxidant serum with microneedling provides superior outcomes for facial rejuvenation than microneedling alone. This combination protocol significantly improves clinical signs of photoaging, including skin elasticity, rhytides, and dyspigmentation, suggesting an optimized treatment protocol with minimal recovery time.
Authors
- Patricia Brieva (ORCID: https://orcid.org/0009-0003-5449-7104)
- Xi Yan (ORCID: https://orcid.org/0000-0002-6732-7038)
- Jihee Kim
- Jemin Kim
- Hyun Ju Kim
- Jihee Boo
Institutions
- University of British Columbia (CA)
- Yonsei University (KR)
- Severance Hospital (KR)
- Psychogenics (United States) (US)
Publication Details
- Journal
- Clinical Cosmetic and Investigational Dermatology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/ccid.s565035
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- L'Oreal USA
- Yonsei University