The impact of B‐cell reconstitution on mRNA vaccine responses in allogeneic stem cell transplant recipients
Our data indicate that mRNA vaccination can stimulate expansion of vaccine-specific B cells to affinity mature in many alloHCT recipients, though restricted by the presence of immature B-cell populations.
Authors
- Anna Nordlander
- Rodrigo Arcoverde Cerveira (ORCID: https://orcid.org/0000-0002-1145-2534)
- Mattias N.E. Forsell (ORCID: https://orcid.org/0000-0001-6904-742X)
- Martin Corcoran (ORCID: https://orcid.org/0000-0002-2774-0936)
- Sebastian Ols (ORCID: https://orcid.org/0000-0001-9784-7176)
- Davide Valentini (ORCID: https://orcid.org/0000-0002-6771-7175)
- Fredrika Hellgren
- P. Ljungman
- Andreas T. Björklund (ORCID: https://orcid.org/0000-0001-7515-2971)
- Alberto Cagigi (ORCID: https://orcid.org/0000-0002-3567-9514)
- Magnus Evander (ORCID: https://orcid.org/0000-0001-6034-4807)
- Klara Lenart (ORCID: https://orcid.org/0000-0002-4984-2618)
- Gunilla B. Karlsson Hedestam (ORCID: https://orcid.org/0000-0001-7255-9047)
- Evangelin Shaloom Vitus
- Gustaf Lindgren (ORCID: https://orcid.org/0000-0002-9992-4371)
- Peter N. Bergman
- Stephan Mielke
- Soo Aleman
- Puran Chen
- Marcus Buggert
- Karin Loré
- COVAXID Study Group
- Yong‐Dae Gwon
- Hans‐Gustaf Ljunggren
- Mireia Rocavert Barranco
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Umeå University (SE)
Publication Details
- Journal
- Clinical & Translational Immunology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cti2.70077
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Washington
- Cancerfonden
- Karolinska Institutet
- Knut och Alice Wallenbergs Stiftelse
- Vetenskapsrådet
- Science for Life Laboratory