A Rare Finding at the Hepaticojejunostomy in a Postliver Transplant Patient

A 30-year-old man with a history of liver transplantation (LT) for primary sclerosing cholangitis presented with a clinical picture compatible with ascending cholangitis. The patient was started on antibiotic therapy, and a magnetic resonance imaging with cholangiopancreatography (MRCP) revealed biliary dilation. The patient then underwent double-balloon endoscopic retrograde cholangiopancreatography (DBE-ERCP). Endoscopic findings revealed an ulcerated mass obstructing the hepatico-jejunostomy (HJ), and biopsies were taken. Pathology was compatible with nondestructive post-transplant lymphoproliferative disorder, and the patient received treatment with rituximab. Eight weeks after treatment, repeat DBE-ERCP showed resolution of the mass and a patent HJ. To our knowledge, this is the first report of a diagnosis of post-transplant lymphoproliferative disorder at the HJ after LT identified with DBE-ERCP.

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Publication Details

Journal
ACG Case Reports Journal
Published
2026-02-01
DOI
https://doi.org/10.14309/crj.0000000000001992
Primary Topic
Viral-associated cancers and disorders
Type
article
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0.00
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article

A Rare Finding at the Hepaticojejunostomy in a Postliver Transplant Patient

John P. Soleas, Aducio Thiesen, Sergio Zepeda-Gómez, Brendan P. Halloran
ACG Case Reports Journal
Viral-associated cancers and disorders
article

A Rare Finding at the Hepaticojejunostomy in a Postliver Transplant Patient

John P. Soleas, Aducio Thiesen, Sergio Zepeda-Gómez, Brendan P. Halloran
article en

Abstract

A 30-year-old man with a history of liver transplantation (LT) for primary sclerosing cholangitis presented with a clinical picture compatible with ascending cholangitis. The patient was started on antibiotic therapy, and a magnetic resonance imaging with cholangiopancreatography (MRCP) revealed biliary dilation. The patient then underwent double-balloon endoscopic retrograde cholangiopancreatography (DBE-ERCP). Endoscopic findings revealed an ulcerated mass obstructing the hepatico-jejunostomy (HJ), and biopsies were taken. Pathology was compatible with nondestructive post-transplant lymphoproliferative disorder, and the patient received treatment with rituximab. Eight weeks after treatment, repeat DBE-ERCP showed resolution of the mass and a patent HJ. To our knowledge, this is the first report of a diagnosis of post-transplant lymphoproliferative disorder at the HJ after LT identified with DBE-ERCP.

ACG Case Reports JournalVol. 13(2)
University of Alberta (CA)
Good health and well-being
Openalex Percentile: Top 59%
Viral-associated cancers and disorders
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