Recurrent Penile and Scrotal Edema as An Extracolonic Manifestation of Metastatic Crohn's Disease in an Adult Patient

We present a case of recurrent penile and scrotal swelling determined to be an extraintestinal manifestation (EIM) of Crohn's disease. Genitourinary complications are a rare EIM, with most cases reported in pediatric populations. Initial treatment assumed cellulitis, delaying appropriate care. Recognition of the swelling as an EIM allowed for targeted treatment with prednisone, leading to rapid resolution. EIMs of Crohn's disease can be difficult to identify, especially rare forms like scrotal and penile edema. Increased awareness and early recognition are essential for streamlined treatment, particularly in adult patients where such presentations are rarely reported in the literature.

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Publication Details

Journal
ACG Case Reports Journal
Published
2026-02-01
DOI
https://doi.org/10.14309/crj.0000000000001996
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
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article

Recurrent Penile and Scrotal Edema as An Extracolonic Manifestation of Metastatic Crohn's Disease in an Adult Patient

Bhanuteja Pujari, Rohit B. Ponnada, Atman K. Shah, Manar Shmais et al.
ACG Case Reports Journal
Autoimmune and Inflammatory Disorders
article

Recurrent Penile and Scrotal Edema as An Extracolonic Manifestation of Metastatic Crohn's Disease in an Adult Patient

Bhanuteja Pujari, Rohit B. Ponnada, Atman K. Shah, Manar Shmais, Atharva M. Bhagwat
article en

Abstract

We present a case of recurrent penile and scrotal swelling determined to be an extraintestinal manifestation (EIM) of Crohn's disease. Genitourinary complications are a rare EIM, with most cases reported in pediatric populations. Initial treatment assumed cellulitis, delaying appropriate care. Recognition of the swelling as an EIM allowed for targeted treatment with prednisone, leading to rapid resolution. EIMs of Crohn's disease can be difficult to identify, especially rare forms like scrotal and penile edema. Increased awareness and early recognition are essential for streamlined treatment, particularly in adult patients where such presentations are rarely reported in the literature.

ACG Case Reports JournalVol. 13(2)
Saint Louis University (US)
Good health and well-being
Openalex Percentile: Top 59%
Autoimmune and Inflammatory Disorders
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