Liver senescence in focus: Heterogeneity across aging and cancer

How does senescent cell heterogeneity vary across different cell types in the liver in aging, fibrosis, and cancer? In Cell Genomics, Karpova and Li et al. reveal cell-type- and context-specific senescent cell signatures, offering the community a valuable resource and providing the potential for future therapeutic innovation.

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Publication Details

Journal
Cell Genomics
Published
2026-02-01
DOI
https://doi.org/10.1016/j.xgen.2026.101168
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Liver senescence in focus: Heterogeneity across aging and cancer

Cleo L. Bishop
Cell Genomics
Telomeres, Telomerase, and Senescence
article

Liver senescence in focus: Heterogeneity across aging and cancer

Cleo L. Bishop
article en

Abstract

How does senescent cell heterogeneity vary across different cell types in the liver in aging, fibrosis, and cancer? In Cell Genomics, Karpova and Li et al. reveal cell-type- and context-specific senescent cell signatures, offering the community a valuable resource and providing the potential for future therapeutic innovation.

Cell GenomicsVol. 6(2)
Queen Mary University of London (GB)
Industry, innovation and infrastructure
Openalex Percentile: Top 58%
Telomeres, Telomerase, and Senescence
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Liver senescence in focus: Heterogeneity across aging and cancer — Cleo L. Bishop · Cell Genomics (2026) | TGRS Research Map | TGRS