The Importance of Ultrasound in Detection of Renal Artery Stenosis
measurement (LSM), respectively.MRE and MRI PDFF served as reference standards for fibrosis and steatosis, respectively.The diagnostic accuracy of simulated FibroScan ROIs was assessed, with agreement analyzed using Cohen's kappa test.Results: Among 118 patients, a strong correlation was observed between simulated FibroScan ROIs and global MRE and PDFF measurements (r = 0.72 and 0.96, respectively; p < 0.0001).However, variability was noted according to fibrosis and steatosis levels.For advanced fibrosis and cirrhosis, FibroScan ROI sensitivity decreased from 91.8% to 83.3%, while specificity and accuracy improved from 75.6% and 85.6% to 95% and 93.2%, respectively.Similarly for steatosis, sensitivity dropped from 89.2% to 88.2%, but specificity and accuracy increased from 86.4% and 87.3% to 99% and 97.5%, respectively.Agreement for LSM ranged from moderate to substantial (0.50-0.75), while for steatosis it ranged from substantial to nearly perfect (0.67-0.89).Conclusions: This study indicates that simulated FibroScan ROIs within an MR exam provide comparable diagnostic accuracy for assessing fibrosis and steatosis as a global liver evaluation.Nonetheless, the effectiveness of these measurements is influenced by the severity of liver disease.
Publication Details
- Journal
- Journal of Ultrasound in Medicine
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/jum.172_70067
- Primary Topic
- Renal and Vascular Pathologies
- Type
- article
- Field-Weighted Citation Impact
- 0.00