Impact of ethnicity and antihyperglycemic medications on dementia incidence in older adults with type 2 diabetes

Ethnic differences in dementia incidence were attenuated after adjustment for demographic and clinical factors. SGLT-2 and DPP-4 inhibitors were associated with a lower risk of dementia, whereas GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors were associated with reduced dementia-related mortality.

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Publication Details

Journal
Endocrine Connections
Published
2026-02-01
DOI
https://doi.org/10.1530/ec-25-0593
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of ethnicity and antihyperglycemic medications on dementia incidence in older adults with type 2 diabetes

S. Ayalon, Elena Chertok Shacham, Muhammad Kadah, Sireen Sharif
Endocrine Connections
Diabetes Treatment and Management
article

Impact of ethnicity and antihyperglycemic medications on dementia incidence in older adults with type 2 diabetes

S. Ayalon, Elena Chertok Shacham, Muhammad Kadah, Sireen Sharif
article en

Abstract

Ethnic differences in dementia incidence were attenuated after adjustment for demographic and clinical factors. SGLT-2 and DPP-4 inhibitors were associated with a lower risk of dementia, whereas GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors were associated with reduced dementia-related mortality.

Endocrine ConnectionsVol. 15(2)
Technion – Israel Institute of Technology (IL), Emek Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 61%
Diabetes Treatment and Management
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