Urinary oxygen partial pressure as a potential biomarker for acute kidney injury: a narrative review

Acute kidney injury (AKI) remains a crucial condition associated with poor prognosis in critically ill patients. Renal oxygenation resulting from renal ischemia is a significant contributor to AKI, wherein urine oxygen partial pressure partially indicates renal medullary oxygenation. The partial pressure of oxygen in urine may serve as a potential biomarker for the prediction and prognosis of AKI. Advances in technology have rendered novel non-invasive and real-time method for urinary oxygen detection. This review examines the significance, detecting method and potential clinical utility of urinary oxygen partial pressure to predict AKI.