<scp>ACSL3</scp> Promotes Hepatocellular Carcinoma Tumorigenesis and Correlates With <scp>JAK</scp> – <scp>STAT3</scp> Signaling

These findings underscore ACSL3 as a significant biomarker and candidate therapeutic target in HCC. Its role bridges dysregulated lipid metabolism with oncogenic signaling and immune evasion, warranting further investigation into ACSL3-targeted strategies.

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Publication Details

Journal
Cancer Medicine
Published
2026-02-01
DOI
https://doi.org/10.1002/cam4.71543
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
Field-Weighted Citation Impact
0.00
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article

ACSL3 Promotes Hepatocellular Carcinoma Tumorigenesis and Correlates With JAK – STAT3 Signaling

Alireza Pourmahdian, Mandana Amelimojarad, Zhang Lu
Cancer Medicine
Peroxisome Proliferator-Activated Receptors
article

ACSL3 Promotes Hepatocellular Carcinoma Tumorigenesis and Correlates With JAK – STAT3 Signaling

Alireza Pourmahdian, Mandana Amelimojarad, Zhang Lu
article en

Abstract

These findings underscore ACSL3 as a significant biomarker and candidate therapeutic target in HCC. Its role bridges dysregulated lipid metabolism with oncogenic signaling and immune evasion, warranting further investigation into ACSL3-targeted strategies.

Cancer MedicineVol. 15(2)
Liaoning University (CN), Iran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 60%
Peroxisome Proliferator-Activated Receptors
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