A Diagonal Earlobe Crease Heralds Intracranial Carotid Artery Atheroscleroctic Plaques on Cone Beam Images; an Acknowledged Cause of Stroke
<h2>Abstract</h2><h3>Objectives</h3> An observational study was conducted to determine if neurologically asymptomatic older males demonstrating a diagonal earlobe crease (DELC); a known "risk factor" for future stroke, predicts the presence of petrous/cavernous segment intracranial internal carotid artery calcified atheroscleroctic plaques (IICACAPs) on dental cone beam computed tomography (CBCT) images. <h3>Study Design</h3> Two <b>maxillofacial radiologists</b> examined facial photographs determining by consensus the presence of DELC+ among 51 male patients (≥55 years). Masked as to DELC status they then determined by consensus the presence of IICACAPs on CBCT images. Finally they queried each participant as to their atherogenic risk factors. <h3>Results</h3> The study group (DELC+) consisted of 31 males (mean age 69.54 ± 8.46) and the control group (DELC-) 20 males (mean age 66.2 ± 6.78). Among the DELC+ patients 19 (67.85%) evidenced IICACAPs on their CBCT whereas among DELC- patients 9 (32.14%) evidenced IICCAPs. Difference in IICACAPs prevalence rates between groups was statistically significant (p=0.0125) as was a history of hypertension denoted mainly in the DELC+ cohort (p=0.033). <h3>Conclusion</h3> Older, hypertensive men with DELC, are significantly more likely to evidence IICACAPs on their CBCT than are those without a crease.
Authors
- Flávia Noemy Gasparini Kiatake Fontão (ORCID: https://orcid.org/0000-0002-3924-7743)
- Luciana Reis Azevedo‐Alanis (ORCID: https://orcid.org/0000-0001-8809-3579)
- Adriana Caroline Leite
- Douglas Augusto Fernandes Couto
- C.A. Machado
- Giulia Fernanda CORREIA
- Elisa Souza Camargo
- Paulo H. Couto-Souza
- Orlando M. Tanaka
- Arthur H. Friedlander
Institutions
- Pontifícia Universidade Católica do Paraná (BR)
- UCLA Medical Center (US)
- Universidade Federal de Santa Catarina (BR)
- Latin American Institute (RU)
- Latin American Sepsis Institute (BR)
Publication Details
- Journal
- Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.oooo.2026.01.027
- Primary Topic
- Reconstructive Facial Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior