Farnesyl Diphosphate Synthase Promotes Proliferation of Hepatocellular Carcinoma Cells by Interacting With Glucose‐6‐Phosphate Dehydrogenase
In summary, this study highlights FDPs play an essential oncogenic role in HCC, linking it to metabolic reprogramming and tumour survival. These findings establish FDPs as a promising therapeutic target, offering a foundation for further exploration of its regulatory mechanisms and potential clinical applications.
Authors
- Xiaohao Hu
- Yan Zhong (ORCID: https://orcid.org/0000-0003-0289-7694)
- Yisheng Zhu
- Jiyang Lv
Institutions
- Peking University Shenzhen Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Shenzhen Institutes of Advanced Technology (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cam4.71620
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shenzhen Science and Technology Innovation Program