Synthesis, Antitumor Activity Evaluation and Mechanistic Study of Novel Bis‐Heterocyclic Chalcones Against Liver Cancer

Bis-heterocyclic chalcone compounds exhibit favorable inhibitory activity against hepatocellular carcinoma cells by inducing cell apoptosis, and thus can serve as a class of pharmaceutically active structural units for further in-depth research and screening.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2026-02-09
DOI
https://doi.org/10.1002/jcla.70154
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
0.00

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article

Synthesis, Antitumor Activity Evaluation and Mechanistic Study of Novel Bis‐Heterocyclic Chalcones Against Liver Cancer

Xiannian Lv, Lei Zhang, Hai Xie, Zhifen Li
Journal of Clinical Laboratory Analysis
Synthesis and biological activity
article

Synthesis, Antitumor Activity Evaluation and Mechanistic Study of Novel Bis‐Heterocyclic Chalcones Against Liver Cancer

Xiannian Lv, Lei Zhang, Hai Xie, Zhifen Li
article en

Abstract

Bis-heterocyclic chalcone compounds exhibit favorable inhibitory activity against hepatocellular carcinoma cells by inducing cell apoptosis, and thus can serve as a class of pharmaceutically active structural units for further in-depth research and screening.

Journal of Clinical Laboratory AnalysisVol. 40(5)
Southern University of Science and Technology (CN), Southern Medical University Shenzhen Hospital (CN), Shenzhen Second People's Hospital (CN), Shanxi Datong University (CN)
Shanxi Datong University
Openalex Percentile: Top 58%
Synthesis and biological activity
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