Implementation of <scp>PlGF</scp> ‐based first‐trimester screening and aspirin prophylaxis for preterm pre‐eclampsia: clinical and economic evaluation
Real-world implementation of PlGF-based screening with aspirin prophylaxis significantly reduced the incidence of preterm pre-eclampsia and preterm birth, and was associated theoretically with substantial health-system cost savings. These findings support consideration of the nationwide adoption of early screen-and-prevent strategies for hypertensive disorders of pregnancy. © 2026 International Society of Ultrasound in Obstetrics and Gynecology.
Authors
- Xin Kang (ORCID: https://orcid.org/0000-0002-1942-1652)
- Dragos Barglazan (ORCID: https://orcid.org/0000-0002-7092-8790)
- Aline Vuckovic (ORCID: https://orcid.org/0000-0001-7412-8259)
- J. C. Jani
- A. Carlin
- D. A. Badr
- T. Cos
Institutions
- Université Libre de Bruxelles (BE)
- Centre Hospitalier Universitaire Brugmann (BE)
- Queen Fabiola Children's University Hospital (BE)
Publication Details
- Journal
- Ultrasound in Obstetrics and Gynecology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1002/uog.70176
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00