Bladder Defect Repair by Polycaprolactone/Gelatin Nanofiber Scaffolds Loaded with Mitomycin Through Anti-Fibrotic Effects
The experimental results demonstrated that PCL/GEL nanofiber materials loaded with 0.02% MMC exhibited excellent biocompatibility and anti-fibrotic effects in bladder defect repair, providing a theoretical basis for their potential clinical application.
Authors
- Haichen Shen
- Jianyou Xia
- Congcong Yang
- Yujie Xu (ORCID: https://orcid.org/0000-0003-3820-2188)
- Renxi Zhu
- Baochao Zhang
- Qiang Wang
- Jianping Tao
- Lunjie Zhao
- Dan Li
Institutions
- Wannan Medical College (CN)
- JiangSu Armed Police General Hospital (CN)
- Central Hospital of Wuhan (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/ijn.s574989
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00