Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?
Although not all participants underwent full diagnostic evaluation, limiting certain analyses, the findings nonetheless underscore the importance of a detailed andrological assessment at the time of diagnosis. This should include semen analysis, hormonal evaluation and ultrasound examination of the contralateral testis to inform personalised fertility preservation strategies. Despite the deterioration in conventional semen parameters, the post-orchidectomy sample demonstrated better DNA integrity and may thus represent the more suitable sample for use in assisted reproductive technologies.
Authors
- Francesco Pallotti (ORCID: https://orcid.org/0000-0001-9946-8516)
- Serena Bianchini
- Carlotta Pozza (ORCID: https://orcid.org/0000-0002-1147-6114)
- Luisa Caponecchia (ORCID: https://orcid.org/0000-0002-0779-6449)
- Anna Chiara Conflitti (ORCID: https://orcid.org/0000-0001-5747-4774)
- Gaia Cicolani (ORCID: https://orcid.org/0000-0003-4629-5222)
- Marta Tenuta (ORCID: https://orcid.org/0000-0002-7476-0737)
- Enrico Delli Paoli (ORCID: https://orcid.org/0000-0003-4866-7130)
- Alessandra Buonacquisto (ORCID: https://orcid.org/0000-0001-6391-2101)
- Donatella Paoli
- Andrea M. Isidori
- Francesco Lombardo
- Daniele Gianfrilli
Institutions
- Bank of Italy (IT)
- Università degli Studi di Enna Kore (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Andrology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1111/andr.70190
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero dell’Istruzione, dell’Università e della Ricerca