Integrative modeling to improve bleeding risk prediction in adult female hemophilia A carriers
Bleeding tendency in HA carriers is common, yet FVIII:C predicts only 38% of those with abnormal bleeding. Logistic regression modeling is highly promising and demonstrates superior performance in predicting bleeding risk compared with baseline FVIII activity alone.
Authors
- Elizabeth A. Weidman
- Peter H. Cygan (ORCID: https://orcid.org/0000-0002-4307-5825)
- Laura Carrel (ORCID: https://orcid.org/0000-0002-5868-4228)
- M.Elaine Eyster
- Xi Wang
- Lan Kong
Institutions
- Pennsylvania State University (US)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.jtha.2026.01.015
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00