<scp> CD56 <sup>bright</sup> </scp> <scp>NK</scp> cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B‐cell‐depleting therapy

Time since ocrelizumab infusion was not associated with protective vaccination. Evaluation of B-cell and CD56<sup>bright</sup> NK cell frequencies may provide a personalised strategy to stratify pwMS for vaccination and prophylaxis.

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Publication Details

Journal
Clinical & Translational Immunology
Published
2026-02-01
DOI
https://doi.org/10.1002/cti2.70079
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

CD56 bright NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B‐cell‐depleting therapy

Sebastian Sterling, Matthew B. Roberts, Makutiro G. Masavuli, Stuart Turville et al.
Clinical & Translational Immunology
Multiple Sclerosis Research Studies
article

CD56 bright NK cells are negatively associated with antibody response to vaccination in people with multiple sclerosis on B‐cell‐depleting therapy

Sebastian Sterling, Matthew B. Roberts, Makutiro G. Masavuli, Stuart Turville, P. Hurtado, Christopher M. Hope, Jacqueline C. Scaffidi, Arthur Eng Lip Yeow, James Zuiani, Janakan Ravindran, Anupriya Aggarwal, Kevin Webb, Joey Yap, Simon C. Barry, Anouschka Akerman, Branka Grubor‐Bauk, Matthew J Tunbridge, Vanessa Milogiannakis, Pravin Hissaria, Griffith B Perkins, Cheng Sheng Chai
article en

Abstract

Time since ocrelizumab infusion was not associated with protective vaccination. Evaluation of B-cell and CD56<sup>bright</sup> NK cell frequencies may provide a personalised strategy to stratify pwMS for vaccination and prophylaxis.

Clinical & Translational ImmunologyVol. 15(2)
South Australia Pathology (AU), Royal Adelaide Hospital (AU), Women's and Children's Hospital (AU), UNSW Sydney (AU), Basil Hetzel Institute (AU), SA Health (AU), The University of Adelaide (AU)
Openalex Percentile: Top 61%
Multiple Sclerosis Research Studies
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