Thrombophilia in Patients with Retinal Vein Occlusion

Multifactorial hereditary thrombophilia was found in patients with retinal vein occlusion in 78.7% of cases, and in 21.3% of cases in combination with lupus anticoagulant (LA). The combination of mutations and polymorphisms in hemostasis genes in patients with retinal vein occlusion (RVO) affects markers of endothelial damage, activating components of the hemostatic system, which clinically manifests as a local thrombohemorrhagic syndrome in the retinal microcirculatory bed.

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Publication Details

Journal
Psychosomatic and Integrative Research
Published
2025-12-30
DOI
https://doi.org/10.15275/pssr.2025.0404
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
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article

Thrombophilia in Patients with Retinal Vein Occlusion

N.Yu. Shishlyannikova, GV Vavin, Т.В. Шелковникова, S.I. Kapustin et al.
Psychosomatic and Integrative Research
Blood Coagulation and Thrombosis Mechanisms
article

Thrombophilia in Patients with Retinal Vein Occlusion

N.Yu. Shishlyannikova, GV Vavin, Т.В. Шелковникова, S.I. Kapustin, Yu.P. Bessonov, Kh.P. Takhchidi
article en

Abstract

Multifactorial hereditary thrombophilia was found in patients with retinal vein occlusion in 78.7% of cases, and in 21.3% of cases in combination with lupus anticoagulant (LA). The combination of mutations and polymorphisms in hemostasis genes in patients with retinal vein occlusion (RVO) affects markers of endothelial damage, activating components of the hemostatic system, which clinically manifests as a local thrombohemorrhagic syndrome in the retinal microcirculatory bed.

Psychosomatic and Integrative ResearchVol. 11(4)
Pirogov Russian National Research Medical University (RU), Kemerovo State Medical University (RU), Kuzbass Institute of Economics and Law (RU), National Medical and Surgical Center named after N.I. Pirogov (RU), Russian Research Institute of Hematology and Transfusiology (RU), Kuzbass State Technical University (RU)
Good health and well-being
Openalex Percentile: Top 21%
Blood Coagulation and Thrombosis Mechanisms
DOISourceOpenAlex
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Thrombophilia in Patients with Retinal Vein Occlusion — N.Yu. Shishlyannikova, GV Vavin, et al. · Psychosomatic and Integrative Research (2025) | TGRS Research Map | TGRS