Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial

Proviral-DNA M184V/I detection was not associated with virological outcomes in participants receiving DTG/3TC supporting its limited clinical value in this specific setting.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2026-02-03
DOI
https://doi.org/10.1093/cid/ciag060
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial

Leandro López, Mayra Jeanneth Saldaña Sigcha, Leire Pérez, Irene Soriano et al.
Clinical Infectious Diseases
HIV/AIDS drug development and treatment
article

Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial

Leandro López, Mayra Jeanneth Saldaña Sigcha, Leire Pérez, Irene Soriano, Christine Vazquez, Sandra Morenilla, Itziar Arrieta, Antonio Ocampo Hermida, Juan Manuel Alonso Martín, Cristina Pérez Algar, Marta de Antonio, Cristina Godoy Cruz, Pilar Callau, José Ramón Arribas, M Ibarguren, Isabel María Huertas Viciana, Victorino Díez, Irene Carrillo, Guillermo Pousada, Xabier Kortajarena, Jennifer Vallejo, Alicia Sedó, Josefa Baliñas, Mireia Santacreu, Margarita Ramírez, R Palacios, Roger Llobet, Rebeca Font, Andoni Casen, Víctor Arribas, C. M. Alvarez, Francisco Redondo Tejerina, Federico Gómez Pulido, Cecilia Canepa, R. Marfil A. Delgado, Laura Lorente Prieto, Miguel Cervero, Pilar Vázquez, Rosa de Miguel, Luz Martín-Carbonero, Mar Masiá, Roser Navarro-Soler, Jesús Troya, Pablo Ryan, Alfonso Cabello, José Sanz, Luis Enrique Morano, Otilia Bisbal, Antonio Ocampo, Celia Miralles, Arkaitz Imaz, VOLVER GESIDA 11820 study group, Juan Carlos López Bernaldo de Quirós, Carlos Meza González, Esteban Martínez, Ignacio de los Santos, Ángela Gutiérrez, Brais Castelo, Asunción Hernando, Mireia Santos, Julen Cadiñanos, Cristina Isabel Torres Hernández, Leire Gil, Araceli Adsuar, Alejandro Araujo, Rafael Torres, Lucio García, Félix Gutiérrez, Aws Waleed, Anna Herranz, Ana Gómez Rodríguez, Jesús Santos, Javier Gorospe García, Adriana Pinto-Martinez, Esperanza Cañas-Ruano, Isabel Gutiérrez, Irene López, Rocío Montejano, Celia Ruiz, Mayra A Sigcha, Henar las Heras, Cristina Diez, Saray Corral, Harkaitz Azkune, Rafael Rubio, María Novella, Teresa Aldamiz, Esther Fagúndez, Marta de Miguel, Andrés Esteban, Sergio Padilla, Mónica Jiménez González, José Luis Blanco, Octavio Arce, María Dolores Martín Escalantey Raúl Quirós López, Inmaculada Burillo, Álvaro Mena, Alicia González, Juanmi Castro, Cristina Hernández Gutiérrez, Marina Garcia, Catalina Robledano, Soledad López, Roser Navarro Soler, Alexandre Pérez, David Rial, Camila Piatti, Alexis Inciarte, Adriana Pinto, Marta Muñoz, Jose Antonio Iribarren, Laura Canals, Ignacio Álvarez, Laura Bermejo, Sergio Gutiérrez, Chiara Fanchiulli, María José Bustinduy, Hernando Knobel
article en

Abstract

Proviral-DNA M184V/I detection was not associated with virological outcomes in participants receiving DTG/3TC supporting its limited clinical value in this specific setting.

Clinical Infectious Diseases
Universidad Complutense de Madrid (ES), Hospital Universitario La Paz (ES), University Hospital Complex Of Vigo (ES), Research Institute Hospital 12 de Octubre (ES), Institut d'Investigació Biomédica de Bellvitge (ES), Centro de Investigación en Red en Enfermedades Cardiovasculares (ES), Hospital La Paz Institute for Health Research (ES), Hospital Universitario Príncipe de Asturias (ES), Hospital Clínic de Barcelona (ES), Fundación Seimc-Gesida (ES), Hospital Universitario de La Princesa (ES), Hospital Del Mar (ES)
Good health and well-being
Openalex Percentile: Top 59%
HIV/AIDS drug development and treatment
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