Clinical Utility and Diagnostic Accuracy of the Gender, Age, α-Fetoprotein, and Des-γ-carboxyprothrombin Score in Non-cirrhotic Patients With Focal Liver Lesions
In this cohort of non-cirrhotic patients with focal liver lesions, the GAAD score was highly predictive of HCC and offered superior diagnostic accuracy over AFP and PIVKA-II alone. These findings support the use of the GAAD score to guide management decisions in these patients.
Authors
- Dave Sprengers (ORCID: https://orcid.org/0000-0003-4280-4210)
- Christian R. B. Ramakers (ORCID: https://orcid.org/0000-0002-5537-6211)
- Vera Ketting
- Mohamed Moussa
- Antonius E. van Herwaarden
- Robert A. de Man
- Milan J. Sonneveld
- Harry L.A. Janssen
- Eric.T.T.L. Tjwa
- Roy S. Dwarkasing
Institutions
- University Health Network (CA)
- Radboud University Nijmegen (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Clinical Gastroenterology and Hepatology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.cgh.2026.01.042
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00