Development and Validation of an Interpretable Machine Learning Model for Predicting Thrombocythemia Risk During Third Generation Cephalosporin Therapy

This interpretable ML framework enables precise thrombocythemia risk prediction during cephalosporin therapy, balancing algorithmic performance with clinical actionability.

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Publication Details

Journal
Journal of Blood Medicine
Published
2026-02-01
DOI
https://doi.org/10.2147/jbm.s567773
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Development and Validation of an Interpretable Machine Learning Model for Predicting Thrombocythemia Risk During Third Generation Cephalosporin Therapy

Maofeng Wang, Kailei Du, Ping Yu
Journal of Blood Medicine
Myeloproliferative Neoplasms: Diagnosis and Treatment
article

Development and Validation of an Interpretable Machine Learning Model for Predicting Thrombocythemia Risk During Third Generation Cephalosporin Therapy

Maofeng Wang, Kailei Du, Ping Yu
article en

Abstract

This interpretable ML framework enables precise thrombocythemia risk prediction during cephalosporin therapy, balancing algorithmic performance with clinical actionability.

Journal of Blood MedicineVol. Volume 17
Wenzhou Medical University (CN), Dongyang People's Hospital (CN)
National Natural Science Foundation of China, Natural Science Foundation of Zhejiang Province
Openalex Percentile: Top 60%
Myeloproliferative Neoplasms: Diagnosis and Treatment
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