Age, sex—and what else? Rethinking priorities to close gaps in the HIV care cascade

It is critically important to generate more efficient strategies to close HIV care cascade gaps and sustain positive progress amidst potentially reduced future resources towards HIV. This may need a paradigm shift in service differentiation that specifically identifies sub-populations most-at-risk of suboptimal outcomes, beyond age/sex categories, while efficiently balancing sub-population size and proportionate risk. Data-driven prioritization of cost-effective interventions targeting the unreached and underserved is essential for sustaining progress in the evolving HIV response.

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Publication Details

Journal
Journal of the International AIDS Society
Published
2026-02-01
DOI
https://doi.org/10.1002/jia2.70080
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00

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article

Age, sex—and what else? Rethinking priorities to close gaps in the HIV care cascade

S ROSEN, Daniel Shodell, Lise Jamieson, Nozipho Musakwa et al.
Journal of the International AIDS Society
HIV/AIDS Research and Interventions
article

Age, sex—and what else? Rethinking priorities to close gaps in the HIV care cascade

S ROSEN, Daniel Shodell, Lise Jamieson, Nozipho Musakwa, M P Fox, Tsitsi Apollo, Idah Mokhele, Domonique M Reed, Peter D. Ehrenkranz, Dorlim Moiana Uetela, Gesine Meyer‐Rath, the Closing The Gap Working Group, Jeffrey W. Imai‐Eaton
article en

Abstract

It is critically important to generate more efficient strategies to close HIV care cascade gaps and sustain positive progress amidst potentially reduced future resources towards HIV. This may need a paradigm shift in service differentiation that specifically identifies sub-populations most-at-risk of suboptimal outcomes, beyond age/sex categories, while efficiently balancing sub-population size and proportionate risk. Data-driven prioritization of cost-effective interventions targeting the unreached and underserved is essential for sustaining progress in the evolving HIV response.

Journal of the International AIDS SocietyVol. 29(2)
Boston University (US), Gates Foundation (US), Center for Disease Dynamics, Economics & Policy (US), University of the Witwatersrand (ZA), Ministry of Health and Child Welfare (ZW), Stellenbosch University (ZA), Media Working Group (US), Instituto Nacional de Saúde (MZ), Imperial College London (GB)
Bill and Melinda Gates Foundation
Good health and well-being
Openalex Percentile: Top 59%
HIV/AIDS Research and Interventions
DOIOpen Access PDFOpenAlex
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Age, sex—and what else? Rethinking priorities to close gaps in the HIV care cascade — S ROSEN, Daniel Shodell, et al. · Journal of the International AIDS Society (2026) | TGRS Research Map | TGRS