Development of a proof‐of‐concept treatment planning system for multi‐beam photon FLASH intensity modulated radiation therapy

FLASHPlan establishes a proof-of-concept TPS framework for multi-beam XFLASH by combining geometry-aware FCRT delivery with biology-aware DMF/BED dose evaluation. Rather than demonstrating therapeutic superiority of FLASH-RT, this work provides a planning infrastructure to support future XFLASH system development, radiobiological modeling, and clinical translation.

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Publication Details

Journal
Medical Physics
Published
2026-02-01
DOI
https://doi.org/10.1002/mp.70331
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Development of a proof‐of‐concept treatment planning system for multi‐beam photon FLASH intensity modulated radiation therapy

Guo Chenlei, Dai Jianrong, Zhu Hongyu, Zhu Meng et al.
Medical Physics
Advanced Radiotherapy Techniques
article

Development of a proof‐of‐concept treatment planning system for multi‐beam photon FLASH intensity modulated radiation therapy

Guo Chenlei, Dai Jianrong, Zhu Hongyu, Zhu Meng, Wang Weiping, Ye Jin, Cui Weijie, Zha Hao, Wang He, Men Kuo, Zhou Yin
article en

Abstract

FLASHPlan establishes a proof-of-concept TPS framework for multi-beam XFLASH by combining geometry-aware FCRT delivery with biology-aware DMF/BED dose evaluation. Rather than demonstrating therapeutic superiority of FLASH-RT, this work provides a planning infrastructure to support future XFLASH system development, radiobiological modeling, and clinical translation.

Medical PhysicsVol. 53(2)
Sun Yat-sen University (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Sun Yat-sen University Cancer Center (CN), Medical Technologies (Czechia) (CZ), State Key Laboratory of Oncology in South China, Tsinghua University (CN)
National Natural Science Foundation of China, National Key Research and Development Program of China
Good health and well-being
Openalex Percentile: Top 56%
Advanced Radiotherapy Techniques
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