Evaluation of hematological parameters as biomarkers of disease activity in drug-naïve patients with rheumatoid arthritis: a retrospective analysis

This study suggests that hematological indices, particularly NLR, PLR, and MPV, hold potential as supplementary biomarkers in RA, but not standalone diagnostic tools. MPV emerged as an independent marker associated with higher disease activity, yet its clinical significance requires further validation. These readily available parameters may be integrated as complementary components of a broader diagnostic and monitoring strategy.