Impact of center‐to‐center distance and slit width on robust target coverage and PVDR for proton minibeam radiation therapy using a commercial TPS
This study demonstrates that robust single-beam pMBRT planning in RayStation is feasible but can be limited by a trade-off between PVDR and robust target coverage, and heavily dependent on beam depth and geometry. These findings provide insights into the effects of beam geometry and collimator parameters on PVDR and robustness, guiding future investigations on robust pMBRT planning.
Authors
- Kelvin Ng Wei Siang (ORCID: https://orcid.org/0000-0003-4315-4870)
- Mischa S. Hoogeman (ORCID: https://orcid.org/0000-0002-4264-9903)
- Erik Tranéus (ORCID: https://orcid.org/0000-0002-1850-7382)
- Anna C. Prins
Institutions
- Proton Therapy Centre (CZ)
- Erasmus MC Cancer Institute (NL)
- RaySearch Laboratories (Sweden) (SE)
Publication Details
- Journal
- Medical Physics
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/mp.70340
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00