Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?

Despite promising advancements in surgical techniques and immunosuppressive regimens, effective nerve regeneration in VCA remains a significant challenge. The variability in clinical outcomes underscores the need for standardized functional assessment protocols and further research into novel regenerative therapies. Future studies should focus on refining these therapeutic strategies to improve long-term functional recovery and minimize the reliance on chronic immunosuppression.

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Publication Details

Journal
Microsurgery
Published
2026-02-01
DOI
https://doi.org/10.1002/micr.70192
Primary Topic
Organ and Tissue Transplantation Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?

Maxime Jeljeli, Felix J Klimitz, Olivier Mathieu, Jakob Fenske et al.
Microsurgery
Organ and Tissue Transplantation Research
article

Where Do We Stand for Nerve Regeneration and Functional Recovery After Vascularized Composite Allotransplantation?

Maxime Jeljeli, Felix J Klimitz, Olivier Mathieu, Jakob Fenske, Thomas Schaschinger, Leonard Knoedler, Alexandre G. Lellouch, Curtis L. Cetrulo
article en

Abstract

Despite promising advancements in surgical techniques and immunosuppressive regimens, effective nerve regeneration in VCA remains a significant challenge. The variability in clinical outcomes underscores the need for standardized functional assessment protocols and further research into novel regenerative therapies. Future studies should focus on refining these therapeutic strategies to improve long-term functional recovery and minimize the reliance on chronic immunosuppression.

MicrosurgeryVol. 46(2)
Cedars-Sinai Medical Center (US), Yale New Haven Hospital (US), Inserm (FR), Université Paris Cité (FR), Humboldt-Universität zu Berlin (DE), Massachusetts General Hospital (US), Hôpital Européen (FR), Paris Cardiovascular Research Center (FR)
Openalex Percentile: Top 62%
Organ and Tissue Transplantation Research
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