Routine use of a spike‐in <scp>DNA</scp> in‐process control for foetal <i>RHD</i> genotyping: Testing the real‐world effectiveness of this ‘canary’
This study demonstrates the prevention of false negative fRHD typing results by the addition of an artificial extraction control. This control allows improved monitoring of assay performance, thereby ensuring assay consistency. Findings underscore the importance of thorough quality assurance measures in fRHD genotyping.
Authors
- Claudia C. Folman (ORCID: https://orcid.org/0000-0003-1346-4202)
- Eric H van Beers (ORCID: https://orcid.org/0000-0003-3566-7350)
- Ahmad Javadi
- Barbera Veldhuisen (ORCID: https://orcid.org/0000-0003-2898-7444)
- Heleen Woortmeijer
- Aïcha Ait Soussan (ORCID: https://orcid.org/0000-0001-9132-7508)
- C. Ellen van der Schoot
- Masja de Haas
- Renske M. van ’t Oever
Institutions
- Leiden University Medical Center (NL)
- Sanquin (NL)
Publication Details
- Journal
- Vox Sanguinis
- Published
- 2026-02-10
- DOI
- https://doi.org/10.1111/vox.70188
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00