Acute ischemic stroke or TIA despite DOAC treatment: the contribution of DOAC plasma levels to understand pathophysiological mechanisms
In DOAC-treated patients with ischemic stroke or TIA, low DOAC levels were found in 2/5 of patients. Lower DOAC levels are associated with increased stroke severity and the presence of LVO/MeVO. The profile of stroke etiology in DOAC-treated patients varies between groups with and without low DOAC levels.
Authors
- Matthias Imöhl (ORCID: https://orcid.org/0000-0002-8372-0251)
- O Nikoubashman
- Marcus Immanuel Rust
- JB Schulz
- Arno Reich
- Martin Wiesmann
- João Pinho
- Merve Gözalan
Institutions
- Forschungszentrum Jülich (DE)
- Evangelisches Krankenhaus Bielefeld (DE)
- Jülich Aachen Research Alliance (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Therapeutic Advances in Neurological Disorders
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1177/17562864261415719
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00