Oral fluoroquinolone use and the risk of aortic and mitral valve regurgitation: a nationwide cohort study

In a nationwide cohort study, there was no statistical support for an increase in the risk of mitral or aortic valve regurgitation associated with oral fluoroquinolone use.

Authors

Malin Inghammar (ORCID: https://orcid.org/0000-0003-2995-1312)
Olof Nibell
Jonas Björk

Institutions

Lund University (SE)
Skåne University Hospital (SE)

Publication Details

Journal: BMJ Open
Published: 2026-02-01
DOI: https://doi.org/10.1136/bmjopen-2024-096783
Primary Topic: Antibiotics Pharmacokinetics and Efficacy
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Skånes universitetssjukhus

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article

Oral fluoroquinolone use and the risk of aortic and mitral valve regurgitation: a nationwide cohort study

Malin Inghammar, Olof Nibell, Jonas Björk

Feb 1, 2026

BMJ Open

Antibiotics Pharmacokinetics and Efficacy

article

Oral fluoroquinolone use and the risk of aortic and mitral valve regurgitation: a nationwide cohort study

Malin Inghammar, Olof Nibell, Jonas Björk

February 1, 2026article en

Abstract

In a nationwide cohort study, there was no statistical support for an increase in the risk of mitral or aortic valve regurgitation associated with oral fluoroquinolone use.

BMJ OpenVol. 16(2)

Lund University (SE), Skåne University Hospital (SE)

Skånes universitetssjukhus

Good health and well-being

Openalex Percentile: Top 60%

Antibiotics Pharmacokinetics and Efficacy

DOI Open Access PDF OpenAlex

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Oral fluoroquinolone use and the risk of aortic and mitral valve regurgitation: a nationwide cohort study — Malin Inghammar, Olof Nibell, et al. · BMJ Open (2026) | TGRS Research Map | TGRS