Ferumoxytol-Enhanced Cardiac Magnetic Resonance for Delineation of Hyperacute Intramyocardial Hemorrhage With Ex Vivo Validation
This proof-of-concept study demonstrates the feasibility and potential of T1-weighted FE-MRI as a unique approach for detecting IMH immediately after ischemia-reperfusion injury. Early identification of IMH by FE-MRI may facilitate translational efforts to develop and evaluate targeted therapies that reduce IMH burden and improve post-AMI outcomes.
Authors
- Jesse W. Currier (ORCID: https://orcid.org/0000-0001-5548-5154)
- Chunni Zhu
- Caroline M. Colbert (ORCID: https://orcid.org/0000-0003-0031-5339)
- Arutyun Pogosyan (ORCID: https://orcid.org/0009-0001-2834-2809)
- Kim-Lien Nguyen
- Mostafa Mahmoudi (ORCID: https://orcid.org/0000-0003-4762-3523)
- Mary Keushkerian
- Aaron C. Llanes
- Gregory A. Fishbein
- J. Paul Finn
- Myung S. Sim
Publication Details
- Journal
- Investigative Radiology
- Published
- 2026-02-10
- DOI
- https://doi.org/10.1097/rli.0000000000001281
- Primary Topic
- Lanthanide and Transition Metal Complexes
- Type
- article
- Field-Weighted Citation Impact
- 0.00