Development and implementation of an MRI‐only simulation, planning, and treatment workflow for prostate radiotherapy using synthetic CT on MR‐linac
The MROSPT workflow using sCT is clinically feasible and dosimetrically accurate for prostate cancer patients. Dose calculations based on sCT demonstrated high dosimetric agreement with simulation CT, with no statistically significant differences across all evaluated metrics. These findings support the adoption of sCT‑based planning for prostate cancer radiotherapy and suggest its potential applicability in other anatomical regions especially in the pelvis. Integration of robust quality‑assurance processes and treatment‑delivery flexibility will further enhance its clinical utility.
Authors
- Surendra K. Prajapati (ORCID: https://orcid.org/0000-0003-1188-668X)
- E. Elaine
- Ergys Subashi (ORCID: https://orcid.org/0000-0001-5168-6928)
- Peter Balter (ORCID: https://orcid.org/0000-0003-4806-8920)
- Reza Reiazi (ORCID: https://orcid.org/0000-0003-1323-8942)
- Eun Young Han
- Jack Yang (ORCID: https://orcid.org/0000-0003-3049-4024)
- Rajat J. Kudchadker (ORCID: https://orcid.org/0000-0003-1978-1014)
- Belinda Lee
- Yao Ding
- Mu‐Han Lin
- Yusung Kim
- Sarath Vijayan
- Hunter L. Emory
- Yao Zhao
- Vi T. Dinh
- Greg L. Swiedom
- Jie Deng
- Seungtaek Choi
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/acm2.70499
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00