The distribution of glycophorin <i>GYP(B‐A‐B)</i> hybrids among blood donors in north‐eastern Thailand

In this study, GYP*Mur was the predominant hybrid allele with a frequency of 254/2754 (9.22%). GYP(B-A-B) hybrid alleles show considerable heterogeneity and immunogenicity, with population-dependent differences driven by variations in antigen distribution and antibody prevalence. The use of our molecular approach may help identify compatible blood products for transfusion and prevent alloimmunization.

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Publication Details

Journal
Vox Sanguinis
Published
2026-02-10
DOI
https://doi.org/10.1111/vox.70202
Primary Topic
Blood groups and transfusion
Type
article
Field-Weighted Citation Impact
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article

The distribution of glycophorin GYP(B‐A‐B) hybrids among blood donors in north‐eastern Thailand

Piyapong Simtong, Patcharaporn Tippayawat, C. Kongmaroeng, SONGPOL HAOHAN et al.
Vox Sanguinis
Blood groups and transfusion
article

The distribution of glycophorin GYP(B‐A‐B) hybrids among blood donors in north‐eastern Thailand

Piyapong Simtong, Patcharaporn Tippayawat, C. Kongmaroeng, SONGPOL HAOHAN, Pornsawan Srichankhot
article en

Abstract

In this study, GYP*Mur was the predominant hybrid allele with a frequency of 254/2754 (9.22%). GYP(B-A-B) hybrid alleles show considerable heterogeneity and immunogenicity, with population-dependent differences driven by variations in antigen distribution and antibody prevalence. The use of our molecular approach may help identify compatible blood products for transfusion and prevent alloimmunization.

Vox Sanguinis
Huachiew Chalermprakiet University (TH), Khon Kaen University (TH)
Openalex Percentile: Top 60%
Blood groups and transfusion
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