Association of left ventricular mass with discordant stress cardiac magnetic resonance and coronary angiography

In patients with suspected obstructive CAD, increased LVM can potentially confound concordance between stress CMR and ICA. This is due to increased microvascular resistance, which decreases the pressure gradient across an epicardial stenosis, resulting in a false high FFR and thus, normal ICA.

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Publication Details

Journal
European Heart Journal - Cardiovascular Imaging
Published
2026-02-05
DOI
https://doi.org/10.1093/ehjci/jeaf350
Primary Topic
Cardiac Imaging and Diagnostics
Type
article
Field-Weighted Citation Impact
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article

Association of left ventricular mass with discordant stress cardiac magnetic resonance and coronary angiography

Christin Isaksen, Jacob Hartmann Søby, Theodore Murphy, Jelmer Westra et al.
European Heart Journal - Cardiovascular Imaging
Cardiac Imaging and Diagnostics
article

Association of left ventricular mass with discordant stress cardiac magnetic resonance and coronary angiography

Christin Isaksen, Jacob Hartmann Søby, Theodore Murphy, Jelmer Westra, Laust Dupont Rasmussen, Morten Bôttcher, Ashkan Eftekhari, L. D. Brix, S Karim, K Kader, Steffen E Petersen, Jonathan Nørtoft Dahl, Simon Winther, Evald Høj Christiansen
article en

Abstract

In patients with suspected obstructive CAD, increased LVM can potentially confound concordance between stress CMR and ICA. This is due to increased microvascular resistance, which decreases the pressure gradient across an epicardial stenosis, resulting in a false high FFR and thus, normal ICA.

European Heart Journal - Cardiovascular ImagingVol. 27(4)
St Bartholomew's Hospital (GB), Aarhus University (DK), Barts Health NHS Trust (GB), Aalborg University Hospital (DK), Aarhus University Hospital (DK), Regionshospitalet Silkeborg (DK), William Harvey Research Institute (GB), Linköping University Hospital (SE)
Openalex Percentile: Top 61%
Cardiac Imaging and Diagnostics
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Association of left ventricular mass with discordant stress cardiac magnetic resonance and coronary angiography — Christin Isaksen, Jacob Hartmann Søby, et al. · European Heart Journal - Cardiovascular Imaging (2026) | TGRS Research Map | TGRS