Preoperative gamma-glutamyl transferase to lymphocyte ratio predicts recurrence in non-muscle-invasive bladder cancer

Preoperative GLR is a simple, cost-effective, and reliable independent biomarker for predicting recurrence in NMIBC patients following TURBt. The GLR-based nomogram integrates systemic inflammation with clinical risk factors, offering a more precise tool for individualized risk stratification. This model can help guide personalized follow-up strategies and adjuvant treatment decisions, holding significant potential for clinical application.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-10
DOI
https://doi.org/10.3389/fonc.2026.1724968
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Preoperative gamma-glutamyl transferase to lymphocyte ratio predicts recurrence in non-muscle-invasive bladder cancer

Xi Zhang, Xiangru Cui, Feifan Song, Yunpeng Cao et al.
Frontiers in Oncology
Inflammatory Biomarkers in Disease Prognosis
article

Preoperative gamma-glutamyl transferase to lymphocyte ratio predicts recurrence in non-muscle-invasive bladder cancer

Xi Zhang, Xiangru Cui, Feifan Song, Yunpeng Cao, Shiqiang Su, Lizhe Liu, Yuanhui Kang, Hanxing He, Chao Li, Jin Zhang, Shen Li
article en

Abstract

Preoperative GLR is a simple, cost-effective, and reliable independent biomarker for predicting recurrence in NMIBC patients following TURBt. The GLR-based nomogram integrates systemic inflammation with clinical risk factors, offering a more precise tool for individualized risk stratification. This model can help guide personalized follow-up strategies and adjuvant treatment decisions, holding significant potential for clinical application.

Frontiers in OncologyVol. 16
Hebei Medical University (CN), First Hospital of Shijiazhuang (CN)
Hebei Provincial Department of Human Resources and Social Security, Health Commission of Hebei Province, Hebei Medical University
No poverty
Openalex Percentile: Top 60%
Inflammatory Biomarkers in Disease Prognosis
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Preoperative gamma-glutamyl transferase to lymphocyte ratio predicts recurrence in non-muscle-invasive bladder cancer — Xi Zhang, Xiangru Cui, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS