A novel oral immunotherapy strategy using transgenic barley induces Culicoides allergen-specific immune responses in horses
The feed-based approach using transgenic barley paste induced Cul o 2p-specific humoral and cellular immune responses in naïve horses, supporting its potential as a scalable and field-feasible platform for prophylactic and therapeutic applications in IBH. Clinical trials in IBH-affected horses are warranted to assess efficacy.
Authors
- Sara Björk Stefánsdóttir (ORCID: https://orcid.org/0000-0001-9560-7574)
- Sigurbjörg Torsteinsdóttir (ORCID: https://orcid.org/0000-0002-3195-4937)
- Sigridur Erla Jonsdottir
- Bettina Wagner (ORCID: https://orcid.org/0000-0003-2370-6324)
- Edelmira Martí (ORCID: https://orcid.org/0000-0002-5678-2916)
- Vilhjálmur Svansson (ORCID: https://orcid.org/0000-0002-3984-4441)
- Fenja Johanna von der Höden
- Dorontina Mahmuti
- Jon Mar Björnsson
Institutions
- University of Bern (CH)
- University of Iceland (IS)
- Cornell University (US)
- Pediatrics and Genetics (US)
- New York State College of Veterinary Medicine (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-10
- DOI
- https://doi.org/10.3389/fimmu.2026.1774358
- Primary Topic
- Veterinary Equine Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00