Endothelial dysfunction and cardiac damage indicators in patients with β-thalassemia major under iron-chelation therapy

β-thalassemia major patients exhibit significant endothelial and cardiac injury markers, altered lipid profiles, and selective upregulation of antioxidant and ferroptosis-related genes.

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Publication Details

Journal
Therapeutic Advances in Hematology
Published
2026-02-01
DOI
https://doi.org/10.1177/20406207261417140
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Endothelial dysfunction and cardiac damage indicators in patients with β-thalassemia major under iron-chelation therapy

Ola M. Al-Sanabra, Manal A. Abbas, Abeer A. Hazàa, Wafà J. Hazà
Therapeutic Advances in Hematology
Hemoglobinopathies and Related Disorders
article

Endothelial dysfunction and cardiac damage indicators in patients with β-thalassemia major under iron-chelation therapy

Ola M. Al-Sanabra, Manal A. Abbas, Abeer A. Hazàa, Wafà J. Hazà
article en

Abstract

β-thalassemia major patients exhibit significant endothelial and cardiac injury markers, altered lipid profiles, and selective upregulation of antioxidant and ferroptosis-related genes.

Therapeutic Advances in HematologyVol. 17
Al-Ahliyya Amman University (JO), Zarqa University (JO), Wenzhou Medical University (CN), Al-Balqa Applied University (JO)
Openalex Percentile: Top 61%
Hemoglobinopathies and Related Disorders
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