The Bushen Huatan formula inhibits TP53-Mediated ferroptosis and modulating lipid metabolism in polycystic ovary syndrome abnormalities rat model
This study demonstrates that BSHT alleviates PCOS pathology by inhibiting ferroptosis and regulating lipid metabolism via the TP53 signaling pathway, providing a theoretical basis for novel therapeutic strategies.
Authors
- Qian Xiong (ORCID: https://orcid.org/0000-0002-0547-039X)
- Lilin Deng
- Xiaofeng Li (ORCID: https://orcid.org/0000-0002-2016-290X)
- Jing Yang
- Xueyuan Hu
- Xiuyong Yue
Institutions
- Chengdu Medical College (CN)
- Chongqing Three Gorges University (CN)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1186/s13048-026-01991-5
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00