The predictive value of a multivariable model based on vaginal Lactobacillus relative abundance and microecological features at 24 weeks gestation and before delivery in spontaneous preterm birth: A Prospective cohort study

At 24 weeks, reduced vaginal LRA is an independent predictor of spontaneous preterm birth. Early vaginal microbiome assessment, combined with clinical features, can help identify high-risk pregnant women and improve outcomes.

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Publication Details

Journal
PLoS ONE
Published
2026-02-10
DOI
https://doi.org/10.1371/journal.pone.0339775
Primary Topic
Preterm Birth and Chorioamnionitis
Type
article
Field-Weighted Citation Impact
0.00
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article

The predictive value of a multivariable model based on vaginal Lactobacillus relative abundance and microecological features at 24 weeks gestation and before delivery in spontaneous preterm birth: A Prospective cohort study

Siling Ren, Xuejuan Xiao, Lingling Jiang, Qingrong Wu et al.
PLoS ONE
Preterm Birth and Chorioamnionitis
article

The predictive value of a multivariable model based on vaginal Lactobacillus relative abundance and microecological features at 24 weeks gestation and before delivery in spontaneous preterm birth: A Prospective cohort study

Siling Ren, Xuejuan Xiao, Lingling Jiang, Qingrong Wu, Tingting Li
article en

Abstract

At 24 weeks, reduced vaginal LRA is an independent predictor of spontaneous preterm birth. Early vaginal microbiome assessment, combined with clinical features, can help identify high-risk pregnant women and improve outcomes.

PLoS ONEVol. 21(2)
Chongqing Maternal and Child Health Hospital (CN), Fuling Center Hospital of Chongqing (CN)
Openalex Percentile: Top 60%
Preterm Birth and Chorioamnionitis
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