Herpes Zoster Risk in Rheumatoid Arthritis Patients on Janus Kinase Inhibitors: A 17-Year Experience from Rheumatoid Arthritis Saudi Database (RASD)

We did not detect any association between JAKi and HZ infection in our RASD. On the other hand, cumulative GC of 60 mg or more and Asian ethnicity were identified as significant risk factors. These findings provide a basis for future nationwide studies aimed to deliver personalized preventive strategies against HZ.

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Publication Details

Journal
Open Access Rheumatology Research and Reviews
Published
2026-02-01
DOI
https://doi.org/10.2147/oarrr.s571893
Primary Topic
Herpesvirus Infections and Treatments
Type
article
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article

Herpes Zoster Risk in Rheumatoid Arthritis Patients on Janus Kinase Inhibitors: A 17-Year Experience from Rheumatoid Arthritis Saudi Database (RASD)

Hanan Almalki, Yasser Bawazir, Reham Kaki, Alhussain Asiri et al.
Open Access Rheumatology Research and Reviews
Herpesvirus Infections and Treatments
article

Herpes Zoster Risk in Rheumatoid Arthritis Patients on Janus Kinase Inhibitors: A 17-Year Experience from Rheumatoid Arthritis Saudi Database (RASD)

Hanan Almalki, Yasser Bawazir, Reham Kaki, Alhussain Asiri, Mohammed AlOmair, Ola Abudaowd, Fida Ahmed, Gamal Salama, Sami Bahlas, Muhammad Siddiqui, Albadr Hussain, Suzan Attar, Hani Almoallim, Ayda Ali, Mona Alsharaif
article en

Abstract

We did not detect any association between JAKi and HZ infection in our RASD. On the other hand, cumulative GC of 60 mg or more and Asian ethnicity were identified as significant risk factors. These findings provide a basis for future nationwide studies aimed to deliver personalized preventive strategies against HZ.

Open Access Rheumatology Research and ReviewsVol. Volume 18
Al-Azhar University (EG), King Abdulaziz University (SA), Umm al-Qura University (SA), King Faisal Specialist Hospital & Research Centre (SA), King Abdullah International Medical Research Center (SA), Soliman Fakeeh Hospital (SA), King Fahad Hospital Jeddah (SA), Asir Central Hospital (SA)
Openalex Percentile: Top 60%
Herpesvirus Infections and Treatments
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Herpes Zoster Risk in Rheumatoid Arthritis Patients on Janus Kinase Inhibitors: A 17-Year Experience from Rheumatoid Arthritis Saudi Database (RASD) — Hanan Almalki, Yasser Bawazir, et al. · Open Access Rheumatology Research and Reviews (2026) | TGRS Research Map | TGRS