Adjuvant PD-1 Inhibitors After Radical Surgery for High-Risk Muscle-Invasive Urothelial Carcinoma: A Systematic Review and Meta-Analysis of Phase 3 Trials
Among patients with resected high-risk MIBC, adjuvant PD-1 inhibitor therapy significantly improves DFS with an acceptable safety profile. However, owing to the limited number of studies and short follow-up periods, these findings should be considered preliminary, and longer follow-up is required to confirm any potential OS benefit.
Authors
- Afef Khanfir
- Wala Ben Kridis
Institutions
- University of Sfax (TN)
- Hopital Universitaire Habib Bourguiba (TN)
Publication Details
- Journal
- Urology Practice
- Published
- 2026-02-10
- DOI
- https://doi.org/10.1097/upj.0000000000000984
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00