The Role of Subjective Well-Being in the Relationship Between Illness Invalidation, Acceptance, and Functioning in Fibromyalgia

Fibromyalgia (FM) is a chronic, widespread pain disorder that severely impairs daily functioning and well-being. Beyond physical symptoms, social and cognitive factors such as illness invalidation and difficulties in acceptance may further hinder adaptation. This study examined whether positive mental health and subjective well-being mediate the relationship between these factors and functioning in women with FM. A total of 148 women aged 20-65 completed self-report measures of the study variables. Preliminary correlation analyses showed that positive mental health was unrelated to invalidation and was therefore excluded from the mediation model. Mediation analyses revealed that higher illness invalidation and greater difficulties in illness acceptance were associated with lower subjective well-being, which in turn related to poorer functioning. These findings highlight the central role of subjective well-being in linking psychosocial factors to functioning in women with FM. Illness invalidation, acceptance difficulties, and subjective well-being itself emerged as key therapeutic targets, underscoring the importance of integrated, acceptance-based, and patient-centered interventions that foster well-being and support adaptive functioning despite persistent symptoms.

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Publication Details

Journal
Behavioral Sciences
Published
2026-02-10
DOI
https://doi.org/10.3390/bs16020259
Primary Topic
Fibromyalgia and Chronic Fatigue Syndrome Research
Type
article
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article

The Role of Subjective Well-Being in the Relationship Between Illness Invalidation, Acceptance, and Functioning in Fibromyalgia

Paola Gremigni, Giulia Casu, Michael Tenti, Carlotta Sansone
Behavioral Sciences
Fibromyalgia and Chronic Fatigue Syndrome Research
article

The Role of Subjective Well-Being in the Relationship Between Illness Invalidation, Acceptance, and Functioning in Fibromyalgia

Paola Gremigni, Giulia Casu, Michael Tenti, Carlotta Sansone
article en

Abstract

Fibromyalgia (FM) is a chronic, widespread pain disorder that severely impairs daily functioning and well-being. Beyond physical symptoms, social and cognitive factors such as illness invalidation and difficulties in acceptance may further hinder adaptation. This study examined whether positive mental health and subjective well-being mediate the relationship between these factors and functioning in women with FM. A total of 148 women aged 20-65 completed self-report measures of the study variables. Preliminary correlation analyses showed that positive mental health was unrelated to invalidation and was therefore excluded from the mediation model. Mediation analyses revealed that higher illness invalidation and greater difficulties in illness acceptance were associated with lower subjective well-being, which in turn related to poorer functioning. These findings highlight the central role of subjective well-being in linking psychosocial factors to functioning in women with FM. Illness invalidation, acceptance difficulties, and subjective well-being itself emerged as key therapeutic targets, underscoring the importance of integrated, acceptance-based, and patient-centered interventions that foster well-being and support adaptive functioning despite persistent symptoms.

Behavioral SciencesVol. 16(2)
Fondazione ISAL (IT), University of Bologna (IT)
No poverty
Openalex Percentile: Top 63%
Fibromyalgia and Chronic Fatigue Syndrome Research
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The Role of Subjective Well-Being in the Relationship Between Illness Invalidation, Acceptance, and Functioning in Fibromyalgia — Paola Gremigni, Giulia Casu, et al. · Behavioral Sciences (2026) | TGRS Research Map | TGRS