Postexercise Lactate Clearance, <scp> <i>T</i> <sub>2</sub> </scp> Relaxation, and <scp> <i>J</i> </scp> ‐Modulation in Human Skeletal Muscle Measured With Double‐Quantum Filtered <scp> <sup>1</sup> H MRS </scp> at 7 T
The new sequence improved lactate detection, enabling quantification from single shots postexercise with time resolution similar to <sup>31</sup>P MRS. Measuring clearance and relaxation time constants of intramuscular lactate lays the groundwork for future absolute quantification and studies of intra- and extracellular lactate compartmentation based on dipolar coupling differences.
Authors
- Roberta Frass‐Kriegl (ORCID: https://orcid.org/0000-0002-8840-4602)
- Martin Meyerspeer (ORCID: https://orcid.org/0000-0002-0295-8218)
- S Trattnig
- Veronika Cap (ORCID: https://orcid.org/0000-0002-2321-4138)
- Kostiantyn Repnin
- Vasco Rafael Rocha dos Santos
- Graham J. Kemp
Institutions
- University of Liverpool (GB)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2026-02-10
- DOI
- https://doi.org/10.1002/mrm.70295
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00