Acute Severe Hepatitis B Virus Infection in Previously Vaccinated Patient during Acalabrutinib Treatment
We describe acute severe hepatitis B virus (HBV) infection with liver failure requiring transplantation in a patient in Poland treated with acalabrutinib. The patient was fully vaccinated against HBV and had adequate HBV antibody titers and no HBV exposure documented before therapy. Differential diagnoses for jaundice should consider HBV in patients receiving acalabrutunib.
Authors
- Hubert Grabowski
- Iwona Marek
- Krystian Adrych (ORCID: https://orcid.org/0000-0001-6476-9095)
- Lukasz Rojek (ORCID: https://orcid.org/0000-0002-0135-3110)
- Tomasz Wnuk-Lipinski
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2026-02-01
- DOI
- https://doi.org/10.3201/eid3202.251111
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00